A Role for Dorsal and Ventral Hippocampus in Inter-Temporal Choice Cost-Benefit Decision Making

model: Group 4 × (Block₄ × S₃₉)], which found a significant main effect of lesion group, F(3, 35) = 2.90; p < .05), but no effect of block, F(3, 105) = 1.09; p = .36, or group × block interaction, F(9, 105) = 1.36; p = .22). Post hoc comparisons (Fisher's LSD test) revealed that the cHPC and vHPC groups chose the HR arm significantly less than the sham group (p < .05). The dHPC group also chose the HR arm less than the shams but this difference was not significant. A separate ANOVA was carried out, directly comparing performance of the dorsal HPC group to the ventral HPC group based on the a priori assumption that different patterns of connectivity to and from these regions implicate the ventral but not dorsal HPC in delayed-based intertemporal choice. However, the ANOVA revealed no difference between the groups, F(1, 18) = 0.35; p = .56) and no group × block interaction, F(3, 54) = 0.41; p = .22.

In the second stage of postoperative testing (Figure 1c), access to food in both the HR and LR arms was subject to a 10s delay. With equal delay in both arms, all groups showed a high and equivalent preference for the HR arm such that by the second block all groups chose the HR on more than 80% of trials. The two blocks of data in the second stage were compared to blocks 3 and 4 from the previous stage