Copyright © 2008 American Psychological Association. Behav Neurosci. 2008 February; 122(1): 1–8. Department of Experimental Psychology, University of Oxford
S. B. McHugh, T. G. Campbell, A. M. Taylor, J. N. P. Rawlins, and D. M. Bannerman
Department of Experimental Psychology, University of Oxford
model: Group 4 × (Block
3 × S
39)], which found no effect of group or block and no interaction (all F
s <1; all p > .7).
Postoperative testing was divided into three stages, as shown in Figure 1. During the four blocks of testing in stage 1, the sham group showed a strong preference for the HR arm. In contrast, the cHPC lesion group showed an increased preference for the LR arm. The partial lesion groups (dHPC and vHPC) also showed an increased preference for the LR arm but to a lesser extent than the cHPC group. Interestingly, the overall chance levels of responding in the cHPC group were largely due to a bimodal pattern of responding: some rats consistently chose the HR arm whereas others consistently chose the LR arm (see also Rawlins et al., 1985). These data were analyzed with a repeated-measures ANOVA